{"product_id":"cosmoperine","title":"Cosmoperine®","description":"\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eCAS No. \u003c\/span\u003e23434-88-0\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eCosmoperine®\u003c\/span\u003e, also known as tetrahydropiperine (THP), is derived from piperine, the active principle of black peppercorns (\u003cspan style=\"font-style: italic;\"\u003ePiper nigrum\u003c\/span\u003e) which acts as a penetration enhancer when added to water soluble ingredients. It works by enhancing the bioavailability of nutrients, including vitamins, minerals, coenzymes, and nutraceutical herbal extracts. An increase in topical permeation was shown when combining Cosmoperine with products like Green Tea extract; an antioxidant rich in polyphenols, Coleus Forskohlli Extract; a skin conditioning agent and Tetrahydrocurcumin; derived from Curcuminoids as extracted from Turmeric Root, acting as a potent antioxidant. One study showed an enhanced absorption of 30% in Vitamin C and Beta Carotene.\u003c\/p\u003e\n\u003cp\u003eWhile at present there is insufficient experimental data to determine the actual mechanism of THP’s bioenhancing properties, it is postulated that THP may operate by increasing either the membrane’s fluidity and\/or the affinity of the nutrient to the cell membrane. THP is also a lipophilic compound and may therefore increase solubilization of the intracellular lipid moiety in the skin, making it more permeable to the applied nutrient.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eINCI:\u003c\/span\u003e Tetrahydropiperine\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-style: italic;\"\u003eCosmoperine® is a patented product of Sabinsa Corporation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-style: italic;\"\u003e\u003cimg alt=\"natural\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/website-symbols-05_100x100.png?v=1585245040\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eCalifornia Prop 65 Statement: \u003c\/span\u003eThe following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.\u003c\/p\u003e\n\u003ch5\u003eSDS \u0026amp; Tech Data\u003c\/h5\u003e\n\u003cp\u003e\u003ca rel=\"noopener noreferrer\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/2004SkinAndItsRoleinProvidingNourishment.pdf?3828893978833510618\" target=\"_blank\"\u003eCosmoperine® as Enhancer of Nutrient and Drug Bioavailability\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/Specification_Sheet_-_Cosmoperine.pdf?v=1748372594\" title=\"Specification Sheet - Cosmoperine\" rel=\"noopener\" target=\"_blank\"\u003eCosmoperine® Specification Sheet\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/Cosmoperine_SDS_GHS.pdf?v=1748372685\" title=\"SDS Cosmoperine\" rel=\"noopener\" target=\"_blank\"\u003eCosmoperine® SDS\u003c\/a\u003e\u003c\/p\u003e\n\u003ch5\u003eFormulation Guide\u003c\/h5\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eRecommended Usage Rate: \u003c\/span\u003e0.001-0.1% (w\/w)\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eAppearance:\u003c\/span\u003e White powder\u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eSolubility:\u003c\/span\u003e Soluble in Dimethyl Isosorbide (2 parts DMI to 1 part Cosmoperine), Ethoxydiglycol and ethanol, partially soluble in propylene glycol, insoluble in water and glycerin\u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eStorage:\u003c\/span\u003e Store in cool, dry place in original container away from light and moisture\u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eShelf life:\u003c\/span\u003e 4 years, 11 months, properly stored.\u003c\/p\u003e","brand":"Undisclosed","offers":[{"title":"5g (0.18 oz) - $9.55","offer_id":13079587651673,"sku":"COSMO-5","price":9.55,"currency_code":"USD","in_stock":true},{"title":"25g (0.88 oz) - $42.25","offer_id":13079587618905,"sku":"COSMO-25","price":42.25,"currency_code":"USD","in_stock":true},{"title":"100g (3.53 oz) - $149.95","offer_id":13079587586137,"sku":"COSMO-100","price":149.95,"currency_code":"USD","in_stock":true},{"title":"500g (17.63oz) - $685.55","offer_id":13079587717209,"sku":"COSMO-500","price":685.55,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/products\/EDTA_575dc8c2-06df-45be-91cc-f2870b3704eb.jpg?v=1571722084","url":"https:\/\/lotioncrafter.live\/products\/cosmoperine","provider":"Lotioncrafter","version":"1.0","type":"link"}