{"product_id":"sepiwhite-msh","title":"Sepiwhite™ MSH","description":"\u003cp\u003eCAS No. 175357-18-3\u003cspan style=\"font-weight: bold; color: #ff0000;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e is an excellent skin lightener and brightener suitable for all skin types and ethnicities that promotes a more uniform and radiant complexion with results in as little as seven days. Studies have demonstrated an increase in skin luminosity and decrease in the number and color of hyperpigmented spots, and it can be combined with other active ingredients, such as niacinamide or AHAs. \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e is a lipoaminoacid or vectorized essential amino acid developed from phenylalanine, an amino acid involved in melanin synthesis. MSH is an alpha-melanocyte-stimulating hormone (MSH) receptor agonist developed from this amino acid that inhibits the process of melanin synthesis from the hypothalamus to produce a reduction in melanic pigments in skin cells.\u003c\/p\u003e\n\u003cp\u003eIn two studies, 1% \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH \u003c\/span\u003ewas combined with 5% niacinamide in lotion. Volunteers reported a reduction in hyperpigmentation after 8 weeks of usage.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIn an eight week study using 2% \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e alone, 83% of volunteers reported a more radiant complexion, 73% fewer age spots, 100% lighter age spots, and 100% more even complexion and skin tone.\u003c\/li\u003e\n\u003cli\u003eIn a seven day study using \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e alone, volunteers reported hyperpigmentation was reduced by 24% and skin luminosity increased by 9%\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e can be combined with a number of other ingredients designed to assist with hyperpigmentation. It can be combined with AHAs to promote a more radiant complexion and more even skin tone. \u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIn studies using 0.2% \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e and 2% ascorbyl glucoside, it doubled the lightening action resulting in a 13% decrease in melanin pigments.\u003c\/li\u003e\n\u003cli\u003eIn a two month study using \u003cspan style=\"font-weight: bold;\"\u003eSepiwhite™ MSH\u003c\/span\u003e alone, skin’s luminosity was increased by +1.13 L*, a measure of skin’s brightness.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eKey Benefits\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePromotes a more uniform and more radiant complexion\u003c\/li\u003e\n\u003cli\u003ePromotes reduction of number and color of age spots\u003c\/li\u003e\n\u003cli\u003eDemonstrated effectiveness for all skin types and ethnicities\u003c\/li\u003e\n\u003cli\u003ePromotes a more even skin tone\u003c\/li\u003e\n\u003cli\u003eReported visible increases in skin luminosity and brightness\u003c\/li\u003e\n\u003cli\u003eECOcert\u003c\/li\u003e\n\u003cli\u003ePreservative free, paraben free phthalate free\u003c\/li\u003e\n\u003cli\u003eReadily biodegradable\u003c\/li\u003e\n\u003cli\u003eNon-phototoxic\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eApplications\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAnti-aging products for face and body, including gels, emulsions, and toners\u003c\/li\u003e\n\u003cli\u003eDaily skin rejuvenating products, like sera, targeted treatments, and moisturizers\u003c\/li\u003e\n\u003cli\u003eRevitalizing products such as toners, gels, masks, and eye products\u003c\/li\u003e\n\u003cli\u003eSkin lightening make-up removers\u003c\/li\u003e\n\u003cli\u003ePressed and loose mineral make-up powders, including foundations and highlighters\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eINCI:\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eUndecylenoyl phenylalanine  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eDisclaimer\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cbr\u003eStatements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.\u003c\/p\u003e\n\u003ch5\u003eSDS \u0026amp; Tech Data\u003c\/h5\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" title=\"Specification Sheet - Sepiwhite™ MSH\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/Specification_Sheet_-_Sepiwhite_MSH.pdf?v=1756830388\" target=\"_blank\"\u003eSepiwhite\u003cspan\u003e™ MSH Specification Sheet\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" title=\"SDS Sepiwhite™ MSH | Lotioncrafter\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/SDS-SEPIWHITE_MSH_-_Seppic.pdf?v=1716487063\" target=\"_blank\"\u003eSepiwhite™ MSH SDS\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/files\/SepiWhite_Millikin.pdf?3520153530641784164\" target=\"_blank\"\u003eSepiwhite™ MSH Research\u003c\/a\u003e\u003c\/p\u003e\n\u003ch5\u003eFormulation Guide\u003c\/h5\u003e\n\u003cp\u003eFormulating Guidelines\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eUse 0.2% in combination with another brightener, otherwise up to 2% in the heated water or heated oil phase of a formulation at more than 60°C (140°F).\u003c\/li\u003e\n\u003cli\u003eIn a product with pH 5 or lower, incorporate into any type of formula.\u003c\/li\u003e\n\u003cli\u003eIn a product above pH 5, but below 6.2, can incorporate with the use of up to 20% ethanol. Not the ideal pH range for this ingredient.\u003c\/li\u003e\n\u003cli\u003eIn a product with pH 6.2 or higher, incorporation into any type of formula is possible.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eCompatibility \u0026amp; Stability\u003c\/span\u003e \u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eExcellent stability in cosmetic products with no expected color or odor changes\u003c\/li\u003e\n\u003cli\u003eCompatible with formulas containing AHA and kojic acid (pH below 5)\u003c\/li\u003e\n\u003cli\u003eCompatible with formulas containing arbutin, hydroquinone, niacinamide, and those above pH 7\u003c\/li\u003e\n\u003cli\u003eCompatible with sunscreens\u003c\/li\u003e\n\u003cli\u003eSuitable for aqueous, hydroalcoholic, or hydroglycolic formulas\u003c\/li\u003e\n\u003cli\u003eSuitable for clear, colorless formulas\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eRecommended Usage Rate: \u003c\/b\u003e0.2 - 2%\u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eSolubility:\u003c\/span\u003e Water soluble at pH 7, otherwise insoluble in water. Miscible in water. Soluble in alcohol and oil. \u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003epH (1% solution in water): \u003c\/span\u003e4.0 \u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eCountry of Origin:\u003c\/span\u003e China \u003cbr\u003e\u003cspan style=\"font-weight: bold;\"\u003eShelf Life:\u003c\/span\u003e 1 year if stored in a cool, dark place\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTry out these formulations using this ingredient:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" title=\"Skin Soothing Toner\" href=\"https:\/\/lotioncrafter.live\/blogs\/natural-formulations\/skin-soothing-toner\" target=\"_blank\"\u003e\u003cspan\u003eSkin Soothing Toner\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Undisclosed","offers":[{"title":"5g (0.17 oz) - $9.95","offer_id":13079660298329,"sku":"SPWHT-5","price":9.95,"currency_code":"USD","in_stock":true},{"title":"25g (0.88 oz) - $29.95","offer_id":13079660265561,"sku":"SPWHT-25","price":29.95,"currency_code":"USD","in_stock":true},{"title":"100g (3.52 oz) - $99.95","offer_id":13079660232793,"sku":"SPWHT-100","price":99.95,"currency_code":"USD","in_stock":true},{"title":"500g (17.63 oz) - $444.95","offer_id":13079660200025,"sku":"SPWHT-500","price":444.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0026\/8317\/5001\/products\/niacinamide_1a663a8e-e493-4bcc-b7bc-3c8732434eec.jpg?v=1571722093","url":"https:\/\/lotioncrafter.live\/products\/sepiwhite-msh","provider":"Lotioncrafter","version":"1.0","type":"link"}